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An Innovative Pioneer in Pharmaceutical Excipients Developed by Zhonglian Chemical
From API processing to formulation forming, and from conventional pharmaceuticals to innovative dosage forms, ZLXIDE 200FP is reshaping the application standards of pharmaceutical excipients with its core advantages of "high efficiency, stability, and safety"
In the R&D and production chain of pharmaceutical preparations, the quality of excipients serves as a critical pillar for the efficacy of pharmaceuticals. ZLXIDE 200FP Silica Excipient, developed by Zhonglian Chemical, leverages its high-purity porous structure and precise adaptability to the entire formulation process to overcome the limitations of traditional excipients. It has become a core material empowering pharmaceutical innovation, providing efficient and reliable excipient solutions for the pharmaceutical industry. Core Properties: Setting a New Benchmark for Excipient Quality The core competitiveness of ZLXIDE 200FP stems from its unique physicochemical characteristics, which create differentiated advantages in the field of pharmaceutical excipients. - High-Purity Porous Structure: As a high-purity amorphous silica micropowder, its well-developed porous structure and ultra-large specific surface area enable efficient adsorption and stabilization of drug molecules.

At the same time, it precisely regulates the drug release process, achieving a balance between drug loading capacity and sustained-release effects. - Precise Particle Size Control: Through advanced processes, it achieves narrow-distribution particle sizes that can adapt to the production needs of multiple dosage forms, including tablets, capsules, and suspensions. It demonstrates excellent compatibility in different formulation systems. - Surface Active Hydroxyl Groups: The dense hydroxyl groups on the surface not only enhance the interfacial bonding force with drug molecules but also significantly improve particle fluidity, optimizing the smoothness of formulation processing from the source. Value Matrix: Empowering the Pharmaceutical Industry Chain in Multiple Dimensions ZLXIDE 200FP creates quantifiable value for the pharmaceutical industry chain from three dimensions: production efficiency, pharmaceutical quality, and medication safety. 1. Production Efficiency Improvement: As a high-efficiency flow promoter, it greatly enhances the fluidity and bulk density of drug particles, reducing issues such as material sticking to punches and caking during production. While lowering equipment wear, it shortens the tablet preparation cycle by more than 15%.

2. Pharmaceutical Quality Optimization: Its excellent moisture absorption and dispersion properties can shorten the drug disintegration time by 30% and increase the drug dissolution rate by 20%. Its chemical inertness ensures the long-term stability of active pharmaceutical ingredients, controlling the drug efficacy attenuation rate within 5% during the validity period. 3. Medication Safety Risk Prevention: The product contains no starch, protein, or other components prone to microbial growth, eliminating the risk of pharmaceutical mildew from the root. Its in vivo metabolic pathway is clear—it is excreted rapidly in its original form without cumulative toxic side effects, fully complying with the ICH Q3D elemental impurity control requirements. Mechanism of Action: Driving Innovation in Formulation Technology Through Science The application effect of ZLXIDE 200FP originates from its in-depth adaptation to formulation processes and multi-functional synergy mechanism. With its small particle size, large specific surface area, and high surface hydroxyl activity, it simultaneously undertakes multiple functions in tablet production, such as lubrication and flow promotion, anti-adhesion, drug adsorption, and crystal form stabilization. In the granulation of oil-based and extract-based drugs, it solves the industry pain points of easy agglomeration and difficult forming of such drugs through the adsorption and dispersion effects of its porous structure. For example, in the preparation of sustained-release tablets, ZLXIDE 200FP can achieve zero-order drug release through gradient design of its porous structure, controlling the fluctuation of blood drug concentration within 20% and significantly improving the sustainability and stability of drug efficacy.

Application Coverage: An Innovative Excipient Adaptable to All Dosage Forms ZLXIDE 200FP has achieved in-depth penetration in various segments of the pharmaceutical preparation field, especially demonstrating outstanding performance in high-difficulty formulation scenarios. - Conventional Tablet Optimization: Addressing the issues of poor fluidity and slow disintegration of traditional tablets, it helps enterprises achieve the dual excellent indicators of "hardness ≥ 120N + dissolution rate ≥ 85% (15min)". - High-End Formulation R&D: In innovative dosage forms such as enteric-coated tablets and pulsatile release formulations, its controllable interfacial properties and stable physicochemical characteristics serve as key excipients for R&D personnel to break through technical bottlenecks. - Special Drug Delivery: For poorly soluble drugs and oil-soluble components, the adsorption and dispersion effects of ZLXIDE 200FP can increase bioavailability by more than 30%. From API processing to formulation forming, and from conventional pharmaceuticals to innovative dosage forms, ZLXIDE 200FP is reshaping the application standards of pharmaceutical excipients with its core advantages of "high efficiency, stability, and safety". It has become a core tool for pharmaceutical enterprises to create differentiated products in the fierce market competition. Would you like me to add a comparative table between ZLXIDE 200FP and traditional silica excipients to this article? It will more intuitively highlight its technical advantages and help readers quickly grasp its core value for Google search indexing.
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